3,6,14,17-Tetramethoxy-22,23-diphenyl-1,10,12,21-tetraazahexacyclo[19.2.1.02,7.010,23.012,22.013,18]tetracosa-2(7),3,5,13(18),14,16-hexaene-11,24-dithione
نویسنده
چکیده
The title compound, C(36)H(34)N(4)O(4)S(2), is a thio-glycoluril derivative, which bears two phenyl substituents on its convex face and two meth-oxy substituted o-xylylenes as sidewalls of the molecular clip. There is one half-mol-ecule in the asymmetric unit: a crystallographic twofold axis generates the complete molecule. The non-planar seven-membered rings adopt chair conformations, while the two five-membered rings exhibit envelope conformations and make a dihedral angle of 68.46 (12)°. The O atoms of the meth-oxy groups are coplanar with the six-membered o-xylylene sidewalls.
منابع مشابه
10,21-Dimethyl-2,7,13,18-tetraphenyl-3,6,14,17-tetraazatricyclo[17.3.1.18,12]tetracosa-1(23),2,6,8(24),9,11,13,17,19,21-decaene-23,24-diol cyclohexane 0.33-solvate
The title compound, C(46)H(40)N(4)O(2)·0.33C(6)H(12), was obtained unintentionally as a product of an attempted synthesis of a cadmium(II) complex of the [2,6-{PhSe(CH(2))(2)N=CPh}(2)C(6)H(2)(4-Me)(OH)] ligand. The full tetra-imino-diphenol macrocyclic ligand is generated by the application of an inversion centre. The macrocyclic ligand features strong intra-molecular O-H⋯N hydrogen bonds. The ...
متن کاملAcyclic Triterpenoids from Alpinia katsumadai Inhibit IL-6-Induced STAT3 Activation.
The seeds of Alpinia katsumadai yielded two new acyclic triterpenoids, 2,3,6,22,23-pentahydroxy-2,6,11,15,19,23-hexamethyl-tetracosa-7,10,14,18-tetraene (3) and 2,3,6,22,23-pentahydroxy-2,10,15,19,23-hexamethyl-7-methylenetetracosa-10,14,18-triene (4), as well as two known compounds, 2,3,22,23-tertrahydroxy-2,6,10,15,19,23-hexamethyl-tetracosa-6,10,14,18-tetraene (1) and 2,3,5,22,23-pentahydrox...
متن کاملThe influence of Schiff base inclusion complexes with β-cyclodextrine on antibiotic production by Streptomyces hygroscopicus CH-7
A media consisting of isatin-Schiff bases and its inclusion complexes with β-cyclodextrine was developed to maximize the production of antibiotics Hexaene H-85 and azalomycine B by Streptomyces hygroscopicus CH-7. The media with β-cyclodextrine inclusion complex of isatin-3-thiosemicarbazone resulted in the maximum antibiotics concentration of 493 μg/cm for Hexaene H-85 and 191 μg/cm for azalom...
متن کاملMetal Complexes of Macrocyclic Schiff-Base Ligand: Preparation, Characterisation, and Biological Activity
A new macrocyclic multidentate Schiff-base ligand Na4L consisting of two submacrocyclic units (10,21-bis-iminomethyl-3,6,14,17-tricyclo[17.3.1.1]tetracosa-1(23),2,6,8,10,12(24),13,17,19,21,-decaene-23,24-disodium) and its tetranuclear metal complexes with Mn(II), Co(II), Ni(II), Cu(II), and Zn(II) are reported. Na₄L was prepared via a template approach, which is based on the condensation reacti...
متن کاملHexaene H-85, a hexaene macrolide complex.
The hexaene macrolide antibiotics constitute the smallest group of the polyenes (12 ~ 1 5). Mediocidin, endomycin, hexaene H-85 and hexafungin each have a significant tetraene spectrum in addition to a hexaene spectrum (hexaene spectrum being predominant) and show high activity against fungi and moderate against Gram-positive bacteria. It was not possible to isolate the separate tetraene and he...
متن کامل